… cause of maternal morbidity and adverse pregnancy outcomes. Adhesion of Plasmodium
falciparum-infected erythrocytes … boundaries of the multi-domain constructs used in this study; …

… of VAR2CSA on the surface of infected erythrocytes, but may … to induce antibodies that
inhibit the binding of infected … antibody mediated inhibition of binding, infected erythrocytes …

… accumulation of Plasmodium falciparum infected erythrocytes (IEs), … Levels of immunoglobulin
G (IgG) antibody in pregnant … Levels of antibodies to baculovirus-expressed VAR2CSA …

… Plasmodium falciparum infected erythrocytes (IE) express VAR2CSA that mediates binding
… Therefore, the induction of anti-adhesive VAR2CSA IgG is the focus for vaccine design. Two …

… It is expressed on the surface of Plasmodium falciparum-infected host red blood cells and …
and multidomain constructs, we have determined the structural architecture of VAR2CSA. The …

… with the cytoadhesive properties of P. falciparum-infected erythrocytes that sequester in the
… However, the amount of surface-presented VAR2CSA adhesin was significantly reduced in …

… of Plasmodium falciparum infected host red blood cells and … Several species of Plasmodium
parasites cause malaria in … non-glycosylated and baculovirus expressed glycosylated …

… VAR2CSA 37 . To obtain high-affinity ofCS binding rVAR2, we produced seven recombinant
fragments of VAR2CSA … The cultures were subsequently induced with 0.1 mM isopropyl-β-d-…

… all Pf Rh2 protein constructs were obtained which were … as they stimulate the immune system
to recognize and induce Abs … of immunoglobulin G antibodies to Plasmodium falciparum …

… Free haem-induced oxidative damage to the endothelium as … of the VAR2CSA variant of
PfEMP1 (Plasmodium falciparum … falciparum-infected erythrocytes were washed in phosphate …